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Home  /  ANZCA Fellowship  /  Study notes  /  Enhanced recovery after surgery — protocol elements, evidence, outcome measures

Enhanced recovery after surgery — protocol elements, evidence, outcome measures

ANZCA Fellowship LO AT_PO 1.6LO AT_PO 2.13LO BT_GS 1.73LO BT_GS 1.71LO AT_GS 1.9LO AT_PO 1.2LO BT_GS 1.75LO AT_GS 1.4LO IT_PO 1.8LO AT_GS 1.7aLO AT_PO 1.9LO IT_GS 1.6LO IT_PM 1.7 2,056 words
Free preview. This study note covers 13 learning objectives (AT_PO 1.6, AT_PO 2.13, BT_GS 1.73, BT_GS 1.71, AT_GS 1.9, AT_PO 1.2, BT_GS 1.75, AT_GS 1.4, IT_PO 1.8, AT_GS 1.7a, AT_PO 1.9, IT_GS 1.6, IT_PM 1.7) from the ANZCA Fellowship curriculum. Inside Primex you get AI-graded SAQ practice on this topic, voice viva with the AI examiner, MCQs across the full syllabus, and a curriculum tracker that ticks off every learning objective.

AT_PO 1.6, ANZCA Fellowship Study Notes


Overview and Context

The traditional model of anaesthetic care, confined to the operating theatre and the immediate perioperative window, is undergoing fundamental transformation. Two complementary frameworks have emerged to address the limitations of fragmented, episodic surgical care: Enhanced Recovery After Surgery (ERAS) and the Perioperative Surgical Home (PSH). Both represent a shift toward coordinated, evidence-based, patient-centred perioperative medicine, and both create expanded professional opportunities for anaesthetists as perioperative physicians.

The impetus for these models arises from several converging pressures: escalating healthcare costs, rising surgical complexity, an opioid epidemic, increasing patient comorbidity, and a healthcare system increasingly focused on value, defined as outcomes achieved per unit cost. These models have demonstrated measurable improvements in outcomes, length of stay (LOS), complication rates, and cost-efficiency across multiple surgical specialties.


Enhanced Recovery After Surgery (ERAS)

Definition and Principles

ERAS protocols are evidence-based, multidisciplinary perioperative care pathways designed to accelerate postoperative convalescence, reduce surgical stress response, minimise complications, and facilitate early functional recovery, without increasing readmission rates.

ERAS represents a paradigm shift: it replaces traditional surgical practices (prolonged fasting, routine bowel preparation, liberal opioid use, routine drains and tubes) with practices validated by high-quality evidence. The fundamental insight is that multiple simultaneous interventions targeting different aspects of the perioperative stress response achieve outcomes that no single intervention can achieve alone.

The concept underpins "fast-track" surgery and involves surgeons, anaesthetists, nurses, physiotherapists, nutritionists, and pharmacists working collaboratively within an integrated pathway.

The Surgical Stress Response: The Central Target

The surgical stress response, mediated by neuroendocrine activation, inflammatory cascades, catecholamine release, and cytokine elaboration, drives postoperative catabolism, ileus, insulin resistance, immunosuppression, and organ dysfunction. ERAS protocols attack this response simultaneously from multiple vectors: attenuating afferent neural signals (regional anaesthesia), minimising the inflammatory trigger (minimally invasive surgery), maintaining metabolic homeostasis (carbohydrate loading, early feeding), and facilitating rapid return of function (early mobilisation, removal of lines and drains).

Critically, good analgesia alone is insufficient to accelerate recovery, because acute pain is only one of many triggers of the injury response. This explains why well-controlled pain with thoracic epidural analgesia (TEA), while providing superior analgesia and earlier return of bowel function, does not consistently shorten LOS or reduce morbidity versus alternative techniques when used within a complete ERAS protocol.

ERAS Protocol Elements

ERAS elements span the full perioperative continuum. The wedge model (Fig. 3.1 in Miller's) illustrates how each phase's interventions influence subsequent phases.

Phase Key ERAS Elements
Preadmission Patient education and goal-setting; medical optimisation; nutritional assessment and support; smoking cessation; alcohol cessation counselling
Preoperative Selective (not routine) bowel preparation; preoperative carbohydrate loading; liberalised fasting (clear fluids until 2 hours preoperatively, light solids until 6 hours); PONV risk assessment and prophylaxis; no prolonged NPO
Intraoperative Minimally invasive surgical approach; regional analgesia; opioid-sparing anaesthesia (consider TIVA); goal-directed fluid management; balanced fluid therapy; active temperature management (normothermia); minimise drains and tubes
Postoperative Early removal of drains, tubes, and urinary catheters; early transition from IV to oral fluids and solids; multimodal opioid-sparing analgesia; early mobilisation; structured postdischarge follow-up

Carbohydrate Loading, Mechanistic Rationale

Preoperative oral carbohydrate drinks (typically a 12.5% carbohydrate solution, 400 mL the evening before and 200 mL 2 hours preoperatively) produce a metabolic anabolic shift with several benefits:

The majority of national and international anaesthetic societies now recommend 6-hour fasting for light non-fatty solids and 2-hour fasting for clear fluids (including carbohydrate drinks).

Evidence for ERAS

ERAS has been most extensively evaluated in colorectal surgery, with robust evidence extending to gynaecology, orthopaedics, hepatobiliary, thoracic, vascular, and neurosurgical procedures. Key outcome data include:

Outcome Evidence
LOS reduction (colorectal) WMD −2.55 days (95% CI −3.24 to −1.85)
Complication rate reduction (colorectal) RR 0.53 (95% CI 0.44 to 0.64)
Nonoperative morbidity reduction (colorectal) 40-50% reduction
LOS reduction (colorectal, absolute) 2-3 days

Elements most strongly associated with shorter LOS in colorectal surgery include: laparoscopic approach, increasing protocol compliance, preoperative carbohydrate and fluid loading, and TIVA. Factors reducing complication risk include restrictive perioperative IV fluids, laparoscopic approach, and increasing overall protocol compliance. Independent predictors of early recovery include enforced early oral intake (normal diet by POD 1-3) and early mobilisation.

Importantly, the number of ERAS elements employed matters, protocols in major trials used between 4 and 12 elements (mean 9). Partial compliance yields attenuated benefit; comprehensive, audited implementation is essential.

Multidisciplinary Team Requirements

The most successful ERAS programs include all healthcare and service providers involved in the perioperative course. This is not optional, the multidisciplinary nature is fundamental to the model's success. Without genuine engagement from surgical, nursing, physiotherapy, pharmacy, and nutrition teams alongside anaesthesia, protocols become fragmented and benefits are lost.

Ongoing outcome measurement, audit, and protocol refinement are essential components. When adverse outcomes occur (e.g. acute kidney injury following implementation of restrictive fluid strategies in some colorectal ERAS protocols), the protocol must be reviewed and modified. This iterative approach, collaborative development, implementation, outcomes review, and modification, underpins the value-based healthcare rationale for ERAS.


Perioperative Surgical Home (PSH)

Definition and Conceptual Framework

The Perioperative Surgical Home is a patient-centred, physician-led model of coordinated care that manages the patient from the time of surgical scheduling through the entire perioperative continuum, including the return to primary care. Developed by the American Society of Anesthesiologists (ASA) in collaboration with other medical specialties, the PSH builds on concepts from the Patient-Centred Medical Home (PCMH) model for outpatient chronic disease management.

The PSH is broader in scope than ERAS. Where ERAS provides specific evidence-based protocol elements within the perioperative window, the PSH is an organisational and care coordination model that encompasses the entire patient journey, including scheduling, preoperative assessment, intraoperative and postoperative management, discharge planning, and transition to primary or community care.

Comparison: ERAS vs PSH

Feature ERAS PSH
Focus Specific evidence-based perioperative protocol elements Whole-of-journey care coordination model
Timeframe Perioperative period (preadmission to postdischarge) Surgical scheduling through return to primary care
Lead Multidisciplinary (no single mandated lead) Often anaesthesiologist-led, but variable
Scope Procedure-specific protocols Broader: patient goals, transitions, chronic disease management
Outcomes targeted LOS, complications, cost, recovery speed Outcomes + patient goals + costs across full continuum
Structural requirement Protocol adherence Organisational model with defined roles and relationships

PSH Goals (as proposed by the ASA)

  1. Identify the patient and proposed surgical plans
  2. Facilitate communication among surgeons, anaesthesiologists, and other providers to coordinate care
  3. Provide thorough preoperative assessment and develop a care plan, including management of associated diseases
  4. Develop and implement evidence-based protocols for clinical care throughout the perioperative period
  5. Manage clinical care across the continuum
  6. Measure and publicly report outcomes and performance

The final goal, public reporting, reflects the PSH's alignment with value-based healthcare and the "triple aim" of improving patient experience, improving population health, and reducing per-capita costs.

The Anaesthesiologist as Perioperative Physician

The PSH creates an expanded professional role for anaesthetists, building on their existing expertise in pathophysiology, pharmacology, monitoring, and perioperative risk. In PSH models where the anaesthesiologist assumes primary coordination responsibility, input from hospitalists and medical subspecialists remains essential to address specific clinical needs.

The PSH also has strategic professional implications: the collaborative relationships built under PSH models increase understanding of anaesthesiologists' skills and value within the health system, and critically position anaesthetists in discussions about bundled payment models and distribution of healthcare funding.

Models and Implementation

There is no single mandated PSH model, implementation varies by health system, institutional relationships, and provider interest. Observed benefits from PSH implementation have included:

Outcome Reported Effect
Surgical cancellations Reduced
Complication rates Reduced
Length of stay Reduced
Readmission rates Reduced

Relationship to the Surgical Hospitalist Model

The surgical hospitalist model, where a hospitalist (surgical or medical) manages non-surgical comorbidities perioperatively, freeing surgeons to focus on operative care, is complementary to but distinct from the PSH. The PSH incorporates clear delineation of roles between anaesthesiologist, hospitalist, and intensivist, particularly during transitions of care (e.g. theatre to ICU, ICU to ward, ward to home). Coordination of these transitions is a core PSH function.


Anaesthetic Implications

Role of the Anaesthetist in ERAS

As a consultant anaesthetist, engagement with ERAS should be proactive and informed. Key intraoperative contributions include:

Domain Specific Practice
Analgesia Multimodal, opioid-sparing approach; regional techniques (neuraxial, peripheral nerve blocks, wound infiltration); avoid unnecessary TEA where alternatives equivalent within ERAS
Anaesthetic technique Consider TIVA (associated with shorter LOS in ERAS registry data, OR 0.86); opioid-free or opioid-reduced techniques
Fluid management Goal-directed fluid therapy; avoid both liberal and overly restrictive approaches; monitor for AKI with restrictive protocols
Temperature Active normothermia maintenance (forced-air warming, fluid warming); hypothermia impairs coagulation, immune function, and wound healing
PONV Systematic multimodal prophylaxis (risk stratification, combination antiemetics, TIVA); PONV is a major barrier to early oral intake and discharge
Fasting Advocate for and implement liberalised fasting guidelines; ensure carbohydrate loading prescribed preoperatively
Lines and tubes Avoid unnecessary nasogastric tubes, urinary catheters, and drains; plan for early removal when required

Role of the Anaesthetist in PSH

Pitfalls and Challenges

Challenge Management Approach
Partial protocol compliance Audit compliance; educate all team members; assign protocol champions
Fluid management extremes Goal-directed therapy; monitor urine output and fluid balance; reassess protocol if AKI signals emerge
Patient not meeting ERAS criteria (e.g. frailty, complex comorbidity) Individualise; PSH model accommodates medical optimisation and specialist input
Opioid-sparing approach in high-complexity pain Robust multimodal plan; anaesthesia-led acute pain service involvement
Resistance from surgical colleagues Collaborative protocol development from the outset; share outcome data; emphasise shared goals
Defining outcome measures Incorporate patient-reported outcomes in addition to LOS and complication rates; ERAS outcomes must be meaningful to patients

Healthcare Economics

ERAS and PSH both represent value-based approaches to perioperative care. Demonstrating value requires measuring outcomes that matter to patients, not just institutional metrics. Future ERAS protocol development must incorporate patient-reported outcome measures (PROMs) to ensure that shorter LOS and fewer complications translate into recovery experiences that patients themselves value.

The PSH model positions anaesthesiology to participate meaningfully in bundled payment models and healthcare funding discussions, a strategic professional opportunity that requires both clinical excellence and outcome data transparency.


Summary

Concept Core Message
ERAS Multimodal, evidence-based perioperative protocol targeting the surgical stress response; benefits require multi-element compliance and multidisciplinary engagement
PSH Anaesthesiologist-facilitated, patient-centred care coordination model spanning surgical scheduling to primary care return; broader than ERAS but complementary
Anaesthetist's role Expanded from intraoperative technician to perioperative physician; leadership in both ERAS protocol development and PSH coordination
Evidence Robust for ERAS in colorectal and multiple other surgical populations; PSH evidence accumulating; both models demonstrate reduced LOS, complications, and cost
Key insight Good analgesia alone is insufficient; comprehensive multimodal protocol compliance is required; patient-reported outcomes must be incorporated

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What patient and procedural factors predict difficult intravenous cannulation?
  • Obesity / significant subcutaneous fat obscuring veins
  • History of IV drug use causing venous scarring and thrombosis
  • Multiple prior cannulations or chemotherapy-related venous damage
  • Dehydration and peripheral vasoconstriction (hypovolaemia, hypothermia, shock)
  • Darkly pigmented skin reducing vein visualisation
  • Paediatric age group, particularly infants and neonates
  • Oedema causing vein burial
  • Raynaud's disease or peripheral vascular disease
  • Anxious or uncooperative patient (venoconstriction from sympathetic activation)
Classify the strategies to increase IV cannulation success rate by category.
  • Patient preparation: warming, hydration, topical vasodilators, venodilation manoeuvres
  • Vein selection optimisation: tourniquet application, gravity-dependent positioning, fist clenching
  • Operator technique: correct bevel orientation, appropriate cannula gauge selection, anchoring skin
  • Adjunct technology: vein visualisation devices (near-infrared, transillumination), ultrasound guidance
  • Pharmacological adjuncts: topical anaesthetics (EMLA, amethocaine), intradermal lidocaine, nitrous oxide
  • Alternative access routes: intraosseous, central venous, ultrasound-guided deep vein access if peripheral fails
How does tourniquet application improve peripheral vein cannulation success?
  • Tourniquet pressure should exceed venous pressure but remain below diastolic arterial pressure
  • Venous outflow is obstructed while arterial inflow continues → vein engorgement
  • Optimal pressure approximately 50–70 mmHg (or firm enough to occlude superficial veins without obliterating radial pulse)
  • Release tourniquet promptly once flashback obtained to avoid haemoconcentration and pain
  • Prolonged tourniquet (>2 min) causes venoconstriction from local hypoxia, counterproductive
What is intraoperative awareness under general anaesthesia?
  • Explicit recall of intraoperative events during intended general anaesthesia
  • May involve auditory, tactile, or painful experiences
  • Can occur with or without explicit memory (implicit vs explicit awareness)
  • Associated with significant psychological morbidity including PTSD
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